In the style of the cliffhanging serials of the 1940s, with the addition of 6 pairs of very big tits and lots of hardcore sex, Mamazon is the story of a lost tribe of women in a forgotten jungle. Four Indiana Jones wanna-bees trek through this mysterious country in search of a mythical stone that has the legendary power to cause phenomenal breast growth. They discover that the legend is all too true when they stumble across this tribe of young, sexy, very busty women who live without men.
The Mamazons are led by their cruel Queen (Alexis Silver), English by birth, who was abandoned in the jungle by her family. She now rules this small band of buxom beauties. Her slave girl is Shyla Shy. The witch doctor of the tribe is Daylene Rio. Alia Janine and Rachel Love are guards, and Kali West is the tribe's ingenue. The men want the stone idol for the wealth they think it can bring if its power can be commercialized.
Their boss, Doctor Jacobs, claims to be a researcher but he may not be what he pretends to be.